Kenac® Tablets: Diclofenac Potassium U.S.P

Overview

Kenac® Tablets contain Diclofenac Potassium, a powerful non-steroidal anti-inflammatory drug (NSAID) that provides effective analgesic and anti-inflammatory relief for various conditions.

Key Features

• Fast-acting relief for mild to severe pain.
• Effective anti-inflammatory action.
• Available in two strengths: 50 mg and 75 mg.

Composition

• Kenac Tablet 50mg: Contains 50 mg of Diclofenac Potassium.
• Kenac Tablet 75mg: Contains 75 mg of Diclofenac Potassium.

Pharmacological Classification

Drug Class:

Non-Steroidal Anti-Inflammatory Drug (NSAID).

Mechanism of Action:

Diclofenac Potassium inhibits prostaglandin synthesis, delivering analgesic, antipyretic, and anti-inflammatory effects.

Indications

Kenac® is prescribed for:

• Mild to moderate pain 🤕.
• Pain and inflammation linked to osteoarthritis and rheumatoid arthritis.
• Post-operative pain (dental and orthopedic surgeries).
• Gynecological inflammatory conditions (e.g., dysmenorrhea).
• Acute migraine episodes.

Contraindications

Avoid using Kenac® if:

• Allergic to Diclofenac or other NSAIDs.
• History of asthma, urticaria, or severe allergic reactions to aspirin.
• Suffering from severe coronary artery disease.

Precautions

• Monitor liver and kidney function during long-term use.
• Be vigilant for gastrointestinal bleeding, especially in patients with a history of ulcers.
• Use with caution in cases of hypertension, heart failure, or renal impairment.

Warnings

1. Cardiovascular Risks: Increased risk of thrombotic events, heart attack, and stroke.
2. Gastrointestinal Effects: Risk of ulcers and bleeding.
3. Renal Impairment: Monitor kidney function closely.
4. Skin Reactions: Serious conditions like Stevens-Johnson Syndrome may occur.

Drug Interactions

• ACE Inhibitors: Reduced antihypertensive effects.
• Diuretics: Potential to decrease renal blood flow.
• Anticoagulants: Increased bleeding risk.
• Lithium, Cyclosporine, Methotrexate: May increase toxicity; monitor closely.

Dosage and Administration

• Mild Pain: 100-150 mg daily in divided doses.
• Primary Dysmenorrhea: 50-150 mg daily, adjusted as needed.
• Migraine: Initial 50 mg at onset, repeat after 2 hours if required (max 200 mg/day).

Adverse Effects

Common (1%-10%):

• Nausea, heartburn, dizziness, headaches.

Serious (Rare):

• Anaphylactic reactions, liver or kidney failure, serious skin reactions.

Storage Instructions

• Store below 25°C.
• Keep away from sunlight, heat, and moisture.
• Out of reach of children.

Presentation

• Kenac Tablet 50mg: Blister pack of 20 film-coated tablets.
• Kenac Tablet 75mg: Blister pack of 20 film-coated tablets.

Conclusion

Kenac® Tablets offer trusted relief from pain and inflammation for a variety of conditions. With its potent NSAID properties, it is a reliable choice for healthcare professionals and patients alike. Always consult a healthcare provider before use.