💊 Copsid Tablets: Tramadol HCl & Paracetamol Combination

Copsid Tablets are formulated to provide effective pain relief through the combination of Tramadol HCl and Paracetamol. This synergistic blend is designed for the short-term management of acute pain, making it an excellent choice for adults and children over 16 years.

Composition (Each Film-Coated Tablet Contains)

• 💊 Paracetamol: 325 mg
• 💊 Tramadol HCl: 37.5 mg

Clinical Pharmacology:

• Mode of Action: Tramadol acts centrally, binding to opioid receptors and inhibiting the re-uptake of norepinephrine and serotonin, while Paracetamol provides analgesic effects.
• Pharmacokinetics:
  • Tramadol peaks in 2-3 hours after oral intake.
  • Paracetamol reaches peak plasma concentration within 1 hour.
  • Both are extensively metabolized in the liver and excreted primarily via the kidneys.

Indications:

• ✨ Short-Term Pain Management: Effective for acute pain relief (less than 5 days).

Dosage and Administration:

• 💡 Recommended:
  • Adults: 2 tablets every 4-6 hours as needed.
  • Maximum: 8 tablets per day.
• ⚠️ Renal Impairment: For patients with creatinine clearance <30 mL/min, do not exceed 2 tablets every 12 hours.

Contraindications:

• Known hypersensitivity to Tramadol or Paracetamol.
• Severe liver impairment.
• Acute intoxication with CNS depressants (alcohol, opioids).
• Use with MAO inhibitors or within two weeks of discontinuation.
• Patients with respiratory depression, increased intracranial pressure, or CNS depression due to head injury.

Adverse Reactions:

• ⚠️ Serious Skin Reactions: Includes AGEP, SJS, and TEN.
• ⚠️ Seizures: Risk increases with higher doses or specific medications.
• ⚠️ Liver Damage: Use cautiously in liver or kidney disease.

Storage Instructions:

• 🌡️ Store: Below 30°C in a cool, dry place. Protect from heat, light, and moisture.
• 🛑 Keep out of reach of children.

Copsid Tablets provide a reliable option for managing acute pain while ensuring patient safety and compliance. Always consult your physician for personalized advice.